The best zodiac signs for labradorite are Leo, Scorpio, and Sagittarius, though it is also considered beneficial for Pisces, Aquarius, and Cancer. Labradorite is associated with these signs due to its properties of transformation, intuition, and spiritual growth, which can complement each sign's unique energies. 
Labradorite's spiritual meaning centers on transformation, protection, and spiritual growth. It is often called the "stone of magic" and is believed to enhance intuition, promote mental clarity, and shield the aura from negative energy. The stone is also associated with the third eye, crown, and throat chakras, supporting psychic abilities and clear communication.